The FX series It's Always Sunny in Philadelphia follows a group of narcissistic friends who own Paddy's Pub in South Philadelphia. The gang frequently conspires to gain money, personal revenge, or just plain attention.

Though the show is primarily filmed in Los Angeles, it features scenes shot around the City of Brotherly Love, including many landmarks that are instantly recognizable to Philadelphia residents. Rob McElhenney, who plays Mac on the show, is a native of Philadelphia, and he regularly brings Philadelphia culture to national audiences with references to Wawa convenience stores, smutty jokes about the city's mayor, and more.

McElhenney and fellow cast members Charlie Day and Glenn Howerton often mention the City of Brotherly Love on their podcast. During the podcast, they have also revealed some behind-the-scenes info about filming, including the fact that the cast and crew are all Eagles fans in real life.

The opening credits of It's Always Sunny in Philadelphia feature a grainy image that was actually taken by actor Charlie Day on his phone as he drove through Philly. The image, combined with footage of historic landmarks such as the Benjamin Franklin Bridge, Swann Memorial Fountain in Logan Circle, and Boathouse Row, immediately establishes Philadelphia as the primary setting for every episode of the sitcom.

The interior shots of Paddy's Pub are filmed in the Nate Starkman & Son building on 544 Mateo Street, while the exterior shots are filmed in various locations throughout Los Angeles. Other locations used for filming include Chandler Valley Center Studios, Alvarado Street, West 11th Street, the alley in West 11th Street near Dickinson and Third, Glendale Boulevard, Lankershim Boulevard, Saticoy Street, and more.