Most Depressed Cities in the US: The Top 10 Revealed

June 6, 2024

Depression is a prevalent mental health issue in the U.S., with significant economic costs, including direct costs, suicide-related costs, and workplace costs. Research suggests that economic growth may actually lead to higher rates of depression, challenging the assumption that a strong economy improves mental health. With this in mind, let's explore some of the cities in the U.S. with the highest depression rates.

1. Detroit, Michigan

Detroit is often highlighted in discussions about high depression rates. Economic hardships and the turmoil in the auto industry have had a long-term impact on the city's mental health landscape. Despite efforts to revitalize the city, many residents continue to face significant challenges that contribute to high depression rates.

Riverfront Plazaa statue in front of a building with a train passing by

2. Cleveland, Ohio

Cleveland faces similar issues with economic instability contributing to mental health concerns. High unemployment rates and the ongoing crisis related to the opioid epidemic have taken a toll on the mental well-being of its residents.

January 2019. Cleveland, OH.high rise buildings near body of water during daytime

3. Toledo, Ohio

Toledo is another Ohio city grappling with high depression rates. The city has experienced economic setbacks, and mental health services are often stretched thin, making it difficult for residents to get the help they need.

"URBAN DEPRESSION AND DECAY IN LIMERICK CITY CENTRE" by infomatique is licensed under CC BY-SA 2.0. To view a copy of this license, visit https://creativecommons.org/licenses/by-sa/2.0/.

4. Birmingham, Alabama

Birmingham struggles with poverty and unemployment rates that contribute to its high depression levels. The city's efforts to improve healthcare infrastructure are ongoing but have not yet significantly ameliorated the situation.

landscape photography of cityscape by water

5. Augusta, Georgia

Augusta has seen rising rates of depression, particularly during the COVID-19 pandemic. Factors such as social isolation, financial insecurity, and limited access to mental health services have exacerbated the problem.

Long exposure capture of Phinizy Swamp, Augusta, Georgia, USA. Visit my website: nilsleonhardt.comgreen trees beside river during daytime

6. Hartford, Connecticut

Economic disparity and social issues are major contributors to the high depression rates in Hartford. The city has been working on initiatives to improve mental health services, but challenges remain.

7. Port St. Lucie, Florida

Port St. Lucie, a city known for its retirement communities, faces unique challenges with depression rates, particularly among older adults. The city's healthcare services are trying to cater to the growing mental health needs of this population.

8. Louisville, Kentucky

Louisville has a high prevalence of depression, influenced by factors such as poverty and lack of mental health resources. The opioid crisis has also significantly impacted the city, contributing to its mental health challenges.

9. Las Vegas, Nevada

Despite being known as a city of entertainment and leisure, Las Vegas has high depression rates. The transient nature of its population, economic pressures, and the impact of the pandemic have all contributed to rising mental health issues.

welcome to fabulous las vegas nevada signage

10. Spokane, Washington

Spokane has one of the highest rates of depression in Washington state. Climatic conditions, economic difficulties, and limited access to mental health resources are significant factors influencing the city's depression rates.

The Myrtle Woldson Performing Arts Center.brown concrete building during nighttime
City State Contributing Factors
Detroit Michigan Economic hardships, auto industry turmoil, long-term impact on mental health landscape
Cleveland Ohio Economic instability, high unemployment rates, opioid epidemic
Toledo Ohio Economic setbacks, stretched mental health services
Birmingham Alabama Poverty, unemployment, healthcare infrastructure improvements ongoing
Augusta Georgia Social isolation, financial insecurity, limited access to mental health services
Hartford Connecticut Economic disparity, social issues, challenges in improving mental health services
Port St. Lucie Florida Challenges among older adults, healthcare services catering to growing mental health needs
Louisville Kentucky Poverty, lack of mental health resources, opioid crisis
Las Vegas Nevada Transient population, economic pressures, impact of the pandemic
Spokane Washington Climatic conditions, economic difficulties, limited access to mental health resources

Which city has the highest depression rate in the US?

While identifying the single city with the highest depression rate can vary based on different studies and criteria, Detroit, Michigan, is frequently highlighted due to its significant economic hardships and long-term impacts on the mental health of its residents.

What are the top 10 most depressed cities in the US?

According to various studies and research, the top 10 most depressed cities in the US are: Detroit, Michigan; Cleveland, Ohio; Toledo, Ohio; Birmingham, Alabama; Augusta, Georgia; Hartford, Connecticut; Port St. Lucie, Florida; Louisville, Kentucky; Las Vegas, Nevada; and Spokane, Washington.

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JJ Sterling
As the co-founder of Urban Splatter and an architecture graduate from Chicago, I thrive on crafting a digital nexus where architectural innovation intersects with boundless digital opportunity. My academic roots in the Windy City's rich architectural tapestry inspire a unique vision for Urban Splatter's journey into the ever-evolving digital frontier of design. Join us as we navigate the exciting confluence of structure, style, and technology.

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